Skin Disorders, Aesthetics and Alopecia
Regenerative medicine and stem cells are being studied for their potential to treat various skin disorders, including scars and ulcers, psoriasis, and alopecia, and for aesthetic purposes.
So far, the results have been promising, with some patients seeing significant improvement in their condition after treatment. However, more research is needed to confirm these treatments’ efficacy and determine the best ways to administer them.
If you are considering stem cell therapy for a skin disorder or other condition, it is essential to consult with a qualified healthcare provider to discuss the risks and benefits.
REFERENCES
1. Li Y, Ye Z, Yang W, Zhang Q, Zeng J. An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases. Stem Cells Int. 2021;2021:8834590. doi: 10.1155/2021/8834590.
2. Golchin A, Farahany TZ, Khojasteh A, Soleimanifar F, Ardeshirylajimi A. The Clinical Trials of Mesenchymal Stem Cell Therapy in Skin Diseases: An Update and Concise Review. Curr Stem Cell Res Ther. 2019;14(1):22-33. doi: 10.2174/1574888X13666180913123424.
3. Bojanic C, To K, Hatoum A, Shea J, Seah KTM, Khan W, Malata CM. Mesenchymal stem cell therapy in hypertrophic and keloid scars. Cell Tissue Res. 2021 Jan 2. doi: 10.1007/s00441-020-03361-z.
4. Guo J, Dardik A, Fang K, Huang R, Gu Y. Meta-analysis on the treatment of diabetic foot ulcers with autologous stem cells. Stem Cell Res Ther. 2017;8(1):228. doi: 10.1186/s13287-017-0683-2.
5. Jiang X, Zhang H, Teng M. Effectiveness of Autologous Stem Cell Therapy for the Treatment of Lower Extremity Ulcers: A Systematic Review and Meta-Analysis. Medicine (Baltimore). 2016;95(11):e2716. doi: 10.1097/MD.0000000000002716.
6. Chen Y, Ma Y, Li N, Wang H, Chen B, Liang Z, et al. Efficacy and long-term longitudinal follow-up of bone marrow mesenchymal cell transplantation therapy in a diabetic patient with recurrent lower limb bullosis diabeticorum. Stem Cell Res Ther. 2018;9(1):99. doi:10.1186/s13287-018-0854-9.
7. Gentile P, Garcovich S. Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects. Int J Mol Sci. 2021;22(4):1538. doi: 10.3390/ijms22041538.
8. Juárez-Navarro KJ, Padilla-Camberos E, Díaz NF, Miranda-Altamirano A, Díaz-Martínez NE. Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2. Stem Cells Int. 2020;2020:8892189. doi: 10.1155/2020/8892189)
9. Paganelli A, Tarentini E, Benassi L, Kaleci S, Magnoni C. Mesenchymal stem cells for the treatment of psoriasis: a comprehensive review. Clin Exp Dermatol. 2020. doi: 10.1111/ced.14269.
10. Niezgoda A, Niezgoda P, Nowowiejska L, Białecka A, Męcińska-Jundziłł K, Adamska U, et al. Properties of skin stem cells and their potential clinical applications in modern dermatology. Eur J Dermatol. 2017;27(3):227-236. doi: 10.1684/ejd.2017.2988.
11. Taub AF, Pham K. Stem Cells in Dermatology and Anti-aging Care of the Skin. Facial Plast Surg Clin North Am. 2018;26(4):425-437.
12. Xiong S, Yi C, Pu LLQ. An Overview of Principles and New Techniques for Facial Fat Grafting. Clin Plast Surg. 2020;47(1):7-17. doi: 10.1016/j.cps.2019.08.001.
13. Epstein GK, Epstein JS. Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss: Current Status. Facial Plast Surg Clin North Am. 2018;26(4):503-511.
14. Semsarzadeh N, Khetarpal S. Platelet-Rich Plasma and Stem Cells for Hair Growth: A Review of the Literature. Aesthet Surg J. 2019. pii: sjz146. doi: 10.1093/asj/sjz146.
15. Tak YJ, Lee SY, Cho AR, Kim YS. A randomized, double-blind, vehicle-controlled clinical study of hair regeneration using adipose-derived stem cell constituent extract in androgenetic alopecia. Stem Cells Transl Med. 2020. doi: 10.1002/sctm.19-0410.
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